Comment on pregnancy and aortic root growth in the Marfan syndrome.

نویسندگان

  • Alfred Hager
  • Harald Kaemmerer
  • John Hess
چکیده

Marsch S, Perruchoud A, Buettner HJ. A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after the placement of coronary artery stents. J Am Coll Cardiol 2003;41:969–973. 6. Wenaweser P, Rotter M, Windecker S, Seiler C, Hess O, Meier B, Eberli F. The phenomenon of late stent thrombosis: differential effect of ticlopidine and clopidogrel. Circulation 2002; 106(suppl.):II-517.

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Pregnancy and aortic root growth in the Marfan syndrome: a prospective study.

AIMS In women with Marfan syndrome pregnancy presents an increased risk of dilatation, dissection, and rupture of the aorta. The aim of this study was to investigate the influence of pregnancy on growth of the aortic root. METHODS AND RESULTS Between 1993 and 2004 127 women with Marfan syndrome were prospectively followed; 61 women had one or more children; in 23 women, 33 pregnancies could b...

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Marfan syndrome in children and adolescents: predictive and prognostic value of aortic root growth for screening for aortic complications.

OBJECTIVE To assess and measure the diagnostic and prognostic value of individual aortic root growth in children and adolescents with Marfan syndrome. DESIGN From 1983 to 1996, 250 children were screened for Marfan syndrome. Serial echocardiographic aortic root measurements of 123 children (57 Marfan, 66 control) were available for evaluation of aortic root growth. Aortic root diameters were ...

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Preventative valve-sparing aortic root replacement and pregnancy outcome in Marfan syndrome.

In Marfan syndrome, with dilatation of the aortic root secondary to an underlying connective tissue defect, pregnancy can cause hemodynamic stress leading to the development of an aortic aneurysm and even a fatal aortic dissection. In the presence of existing aortic root enlargement and a family history of aortic dissection, preventative elective surgery is suggested. Aortic root replacement wi...

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Sex, pregnancy and aortic disease in Marfan syndrome

BACKGROUND Sex-related differences as well as the adverse effect of pregnancy on aortic disease outcome are well-established phenomena in humans with Marfan syndrome (MFS). The underlying mechanisms of these observations are largely unknown. OBJECTIVES In an initial (pilot) step we aimed to confirm the differences between male and female MFS patients as well as between females with and withou...

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عنوان ژورنال:
  • European heart journal

دوره 26 21  شماره 

صفحات  -

تاریخ انتشار 2005